Snyder P.M., Martin J., Herman J.J., Franklin S., Wagoner K.M., Soroker V., Rueppell O. (2024) The impact of honey bee (Apis mellifera) group size on hygienic behavior performance. Behavioral Ecology and Sociobiology, 78:52. Link.

Reams T., Rueppell O., Rangel J. (2024) Honey bee (Apis mellifera) nurse bee visitation of worker and drone larvae increases Varroa destructor mite cell invasion. Journal of Insect Science, 24:16. Link.

Walton A, Herman J.J., Rueppell O (2024) Social life results in social stress protection: A novel concept to explain individual life history patterns in social insects. Biological  Reviews Link.

Han B., Wu J., Wei Q., Liu F., Cui L., Rueppell O., Xu S. (2024) Life-history stage determines within-host dietary alternation of ectoparasitic mites. Nature Communications, 15:725. Link.


Rueppell O., Walton A. Social foraging of the honey bee colony. In: “The Foraging Behavior of the Honey Bee (Apis mellifera, L.)”, J. Purdy (ed.) Academic Press. ISBN: 978-0323917933, p. 65-83. Link

Han B., Amiri E., Wei Q., Tarpy D.R., Strand M.K., Xu S., Rueppell O. Group size influences maternal provisioning and compensatory larval growth in honey bees. iScience 26, 10854. Link

Lu RX, Bhatia S, Simone-Finstrom M, Rueppell O. Quantitative trait loci mapping for survival of virus infection and virus levels in honey bees. Infection, Genetics and Evolution 116, 105534. Link

Bahreini R., Docherty C.,Feindel D., Muirhead S. Comparing the efficacy of synthetic Varroacides and Varroa destructor phenotypic resistance using Apiarium and Mason jar bioassay techniques. Pest Management Science Link.

Fang Y., Feng M., Ma C., Rueppell O., Li J. Major royal jelly proteins influence the neurobiological regulation of the division of labor among honey bee workers. International Journal of Biological Macromolecules 225:848-860. Link


Han B., Wei Q., Amiri E., Hu H., Meng L., Strand M.K., Tarpy D.R., Xu S., Li J., Rueppell O. The molecular basis of socially induced egg-size plasticity in honey bees. eLife 11:e80499. Link

Chapman A., Amiri E., Han B., McDermott E., Rueppell O., Tarpy D.R., Foster L.J., McAfee A. Fertility costs of cryptic viral infections in a model social insect. Scientific Reports 12:15857. Link

Erez T., Bonda E., Kahanov P., Rueppell O., Wagoner K.M., Chejanovsky N., Soroker V. Multiple benefits of breeding honey bees for hygienic behavior. Journal of Invertebrate Pathology 193:107788. Link

Waiker P., Ulus Y., Tsui MTK, Rueppell O. Mercury accumulation in honey bees trends upward with urbanization in the USA. Agricultural & Environmental Letters 7:e20083. Link

Simone-Finstrom M., Strand M.K., Tarpy D.R., Rueppell O. Impact of honey bee migratory management on pathogen loads and immune gene expression is affected by complex interactions with environment, worker life history, and season. Journal of Insect Science, 22: 17; 1–10. Link


Wagoner K.M., Spivak M., Millar J., Keller J., Waiker P., Schal C., Rueppell O. Hygiene-eliciting brood semiochemicals as a tool for assaying honey bee (Hymenoptera: Apidae) colony resistance to Varroa (Mesostigmata: Varroidae). Journal of Insect Science, 21(6):4; 1-13. Link

Waiker P., de Abreu F.C.P., Luna-Lucena D., de Paula Freitas F.C., Simoes Z.L.P., Rueppell O. Recombination mapping of the Brazilian stingless bee Frieseomelitta varia confirms high recombination rates in social Hymenoptera. BMC Genomics, 22:673. Link

Damico M.E., Rueppell O., Shaffer Z., Han B., Raymann K. High royal jelly production does not impact the gut microbiome of honey bees. Animal Microbiome, 3: 60. Link

Fouks B., Brand P., Nguyen H.N., Herman J., Camara F., Ence D., Hagen D.E., Hoff K.J., Nachweide S., Romoth L., Walden K.K.O., Guigo R., Stanke M., Narzisi G., Yandell M., Robertson H.M., Koeniger N., Chantawannakul P., Schatz M.C., Worley K.C., Robinson G.E., Elsik C.G., Rueppell O. The genomic basis of evolutionary differentiation among honey bees. Genome Research, 31: 1203-1215. Link

Amiri E., Rueppell O., Tarpy D.R.  Chapter 21: Honey Bee Viral Diseases. In: “Honey Bee Medicine for the Veterinary Practitioner”, T.R. Kane & C.M. Faux (eds), Wiley Blackwell. ISBN: 978-1-119-58337-0. Link

Han B., Wei Q., Wu F., Hu H., Ma C., Meng L., Zhang X., Feng M., Fang Y., Rueppell O., Li J. Tachykinin signaling inhibits task-specific behavioral responsiveness in honeybee workers. eLife, 10: e64830. Link

Kennedy A., Herman J.J., Rueppell O. Reproductive activation in honey bee (Apis mellifera) workers protects against abiotic and biotic stress. Philosophical Transactions of the Royal Society B, 376: 20190737. Link

Bhatia S., Baral S.S., Vega Melendez C., Amiri E., Rueppell O. Comparing survival of Israeli acute paralysis virus infection among stocks of U.S. honey bees. Insects, 12(1): 60. Link.

Barrs K.R., Ani M.O., Eversman K.K., Rowell J.T., Wagoner K.M., Rueppell O. Time-accuracy trade-off and task partitioning of hygienic behavior among honey bee (Apis mellifera) workers. Behavioral Ecology and Sociobiology, 75:12, Link.


Amiri E., Herman J.J., Strand M.K., Tarpy D.R., Rueppell O. Egg transcriptome profile responds to maternal virus infection in honey bees, Apis melliferaGenetics and Evolution, 85:104558. Link

Li-Byarlay H., Boncristiani H., Howell G., Herman J., Clarke L., Strand M.K., Tarpy D.R., Rueppell O. Transcriptomic and epigenomic dynamics of honey bees in response to lethal viral infection. Frontiers in Genetics, 11:566320. Link

Zhang X., Hu H., Han B., Wei Q., Meng L., Wu F., Fang Y., Feng M., Ma C., Rueppell O., Li J. The neuroproteomic basis of enhanced perception and processing of brood signals that trigger increased reproductive investment in honeybee (Apis mellifera) workers. Molecular and Cellular Proteomics, 19(10): 1632-1648. Link

Amiri E., Waiker P., Rueppell O., Manda P. Using manual and computer-based text-mining to uncover research trends for Apis mellifera. Veterinary Sciences, 7:61. Link

Wagoner K.M., Millar J., Schal C., Rueppell O.  Cuticular pheromones stimulate hygienic behavior in the honey bee (Apis mellifera). Scientific Reports, 10: 7132. Link

Amiri E., Strand M.K., Tarpy D.R., Rueppell O. Honey bee queens and virus infections. Viruses, 12(3): 322. Link

Amiri E., Le K., Vega-Melendez C., Strand M.K., Tarpy D.R., Rueppell O. Egg-size plasticity in Apis mellifera: honey bee queens alter egg size in response to both genetic and environmental factors. Journal of Evolutionary Biology,33(4): 534-543. Link

Oppenheim S., Cao X., Rueppell O., Chantawannakul P., Krongdang S., Phokasem P., DeSalle R., Goodwin S., Xing J., Rosenfeld J. Whole Genome Sequencing and Assembly of the Asian Honey Bee Apis dorsata. Genome Biology and Evolution, 12(1): 3677-3683. Link

Wagoner K.M., Rueppell O.  U.S Patent No. 10,524,455 B2: Methods and Compositions for Inducing Hygienic Behavior in Honey bees.

DeLory T., Funderburk K., Miller K., Zuluaga-Smith W., McPherson S., Pirk C.W., Costa C., Weinstein-Teixeira E., Dahle B., Rueppell O. Local variation in recombination rates of the honey bee (Apis mellifera) genome among samples from six disparate populations. Insectes Sociaux, 67(1):  127-138. Link


Wagoner K.M., Rueppell O. U.S Patent No. 10,512,251 B2: Methods and Compositions for Inducing Hygienic Behavior in Honey bees.

Wagoner K.M., Spivak M., Hefetz A., Reams T., Rueppell O. Varroa mites and Deformed Wing Virus elicit hygienic behavior in honey bees through stock-specific changes in brood cuticular hydrocarbons. Scientific Reports, 9: 8753. Link

Amiri E., Seddon G., Zuluaga-Smith W., Strand M.K., Tarpy D.R., Rueppell O. Israeli Acute Bee Paralysis Virus: queen-worker interaction and potential virus transmission pathways. Insects, 10(1): 9. Link

Wu F., Ma C., Han B., Meng L., Hu H., Fang Y., Feng M., Zhang X., Rueppell O., Li J., (2019) Behavioral, physiological, and molecular changes in alloparental care givers may be responsible for selection response for female reproductive investment in honey bees. Molecular Ecology, 28: 4212-4227. Link

Waiker P., Baral S., Kennedy A., Bhatia S., Rueppell A., Le K., Amiri E., Tsuruda J., Rueppell O. Foraging and homing behavior of honey bees (Apis mellifera) during a total solar eclipse. The Science of Nature, 106:4. Link

Rueppell O., Kennedy A. Aging and Behavior in Honey Bees. In: “Encyclopedia of Animal Behavior, Second Edition”, J. Choe (ed.), Academic Press, ISBN13: 978-0128132517.


Amiri E., Kryger P., Meixner M.D., Strand M.K., Tarpy D.R., & Rueppell O. Quantitative patterns of vertical transmission of deformed wing virus in honey bees. PLoS One, 13(3): e0195283. Link 

Wagoner K.M., Spivak M., Rueppell O. Brood affects hygienic behavior in the honey bee (Hymenoptera: Apidae). Journal of Economic Entomology, 111(6): 2520-2530. Link

Lawhorn C.M., Shomaker R., Rowell J.T., & Rueppell O. Simple comparisons of differentially expressed gene lists may overestimate gene overlap. Journal of Computational Biology, 25(6). 606-612. Link

Quigley T.P., Amdam G.V., Rueppell O. Honey bee workers as models of aging. In: “Conn’s Handbook of Models for Human Aging”, J. Ram (ed.), Elsevier Press, Atlanta, p.533-547. Link

Langberg K., Phillips M., Rueppell O. Testing the effect of paraquat exposure on genomic recombination rates in queens of the Western Honey Bee, Apis mellifera. Genetica, 146(2), 171-178. Link


Amiri E., Strand M.K., Rueppell O. & Tarpy D.R. Queen quality and the impact of honey bee diseases on queen health: potential for interactions between two major threats to colony health. Insects, 8(2), 48. Link

Rueppell O., Yousefi B., Collazo J. & Smith D. Early life stress affects mortality rate more than social behavior, gene expression or oxidative damage in honey bee workers. Experimental Gerontology, 90: 19-25. Link

Wagoner K.M. & Rueppell O. Effects of steel foundation wire on elemental content and hygienic removal of honey bee (Apis mellifera) brood. Journal of Apicultural Research, 56(3):270-277. Link


Rueppell O., Kuster R. , Miller K. , Fouks B., Rubio Correa S., Collazo J., Phaincharoen M., Tingek S., & Koeniger N. A new metazoan recombination rate record and consistently high recombination rates in the honey bee genus Apis accompanied by frequent inversions but not translocations. Genome Biology and Evolution, 8(12): 3653-3660. Link

Simone-Finstrom M., Li-Byarlay H., Huang M.H., Strand M.K., Rueppell O., & Tarpy D.R. Migratory management and environmental conditions affect lifespan and oxidative stress in honey bees. Scientific Reports, 6: 32023. Link

Li-Byarlay H., Huang M.H., Simone-Finstrom M., Strand M.K., Tarpy D.R., & Rueppell O. Honey bee (Apis mellifera) drones survive oxidative stress due to increased tolerance instead of avoidance or repair of oxidative damage. Experimental Gerontology, 83(10): 15-21. Link

Rueppell O., Aumer D. & Moritz R.F.A. Ties between aging plasticity and reproductive physiology in honey bees (Apis mellifera) reveal a positive relation between fecundity and longevity as consequence of advanced social evolution. Current Opinion in Insect Science, 16: 64-68. Link


Thompson E., Everett J., Rowell J.T., Rychtar J. & Rueppell O. The evolution of cooperation is affected by the persistence of fitness effects, the neighborhood size and their interaction. Letters in Biomathematics, 2(1): 67-78. Link

von Wyschetski K., Rueppell O., Oettler J. & Heinze J. Transcriptomic signatures mirror the lack of the fecundity / longevity trade-off in ant queens. Molecular Biology and Evolution, 32(12): 3173-3185. Link

Rueppell O., Koenigseder F., Heinze J. & Schrempf A. Intrinsic survival advantage of social insect queens depends on reproductive activation. Journal of Evolutionary Biology, 28(12): 2349-2354. Link

Sadd B.M., Barribeau S.M., et al. (List of 142 Authors including Rueppell, O.) The genomes of two key bumblebee species with primitive eusocial organization. Genome Biology, 16:76. Link

Ross C., DeFelice D., Hunt G., Ihle K., Amdam G.V. & Rueppell O. Genomic correlates of recombination rate and its variability across eight recombination maps in the Western Honey Bee (Apis mellifera L.). BMC Genomics, 16:107. Link

Ihle K.E., Rueppell O., Huang Z.Y., Wang Y., Fondrk M.K., Page R.E., Amdam G.V. Genetic architecture of a hormonal response to gene knockdown in honey bees. Journal of Heredity,106: 155-165. Link

Michaud S., Boncristiani H.F., Gouw J.W., Strand M., Pettis J., Rueppell O., Foster L.J. Response of the honey bee (Apis mellifera L.) proteome to Israeli acute paralysis virus infection. Canadian Journal of Zoology, 93(9): 711-720. Link

Ross C., Rychtar J., Rueppell O. A structured population model suggests that long life and post-reproductive lifespan promote the evolution of cooperation. Journal of Theoretical Biology, 369:85-94. Link

Ross C., DeFelice D., Hunt G., Ihle K., Rueppell O. A comparison of multiple genome-wide recombination maps in Apis mellifera. Springer Proceedings in Mathematics & Statistics 109: 91-98. Link

DeFelice D.S., Ross C., Simone-Finstrom M., Warrit N., Smith D.R., Burgett M., Sukumalanand P., Rueppell O. Geographic variation in polyandry of the Eastern Honey Bee, Apis cerana, in Thailand. Insectes Sociaux, 62(1): 37-42, Link